ModiQuest Research has developed an efficient mix of anti-collagen antibodies for the generation of a collagen antibody induced arthritis (CAIA) mouse animal model. The CAIA model is ideal for rapid screening of novel arthritis therapeutics and to study the mechanisms involved in the development of arthritis.
Main advantages of our model:
- severe arthritis is induced within 24-48 hours instead of 4 weeks
- ideal for rapid screening of therapeutics for the treatment of arthritis
- ideal to study the mechanisms involved in the development of arthritis.
Animal Studies Using The CAIA Arthritis Mouse Model
For researchers in the rheumatoid arthritis field, we test anti-inflammatory small molecule, antibody or peptide therapeutic candidates. Our range of efficacy readouts, include:
- macroscopic evaluations
- histology
- serology
- cytokine pathway analysis
Alternatively, the CAIA antibodies can be delivered directly to clients for in-house animal model generation. See our Arthritis Antibody Mix Product Page for more information.
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